In recent years, with the rising numbers of stem cell transplantation and solid organ transplant recipients; increasing use of excessively high dose immunosuppressant and aggressive chemotherapy; widespread use of interventional therapy and indwelling of catheter, the incidence of invasive fungal diseases (IFD) have increased significantly. IFD becomes a major cause of death and severe complications for patients who receive bone marrow or organ transplant and patients who receive chemotherapy due to malignant hematopathy and tumor, AIDS patients and those in critical conditions. Diagnosis of invasive mycoses usually involves non-specific diagnostic or radiological techniques.
(1-3)-β-D-Glucan is the main cell wall component of most fungi, such as Candida, Aspergillus and Fusarium, etc. and does not exist in bacteria, virus or human cells.
Fungus (1-3)-β-D-Glucan Assay is based on spectrophotometry for the quantitative detection of (1-3)-β-D-Glucan in human serum. It offers a diagnostic reference for invasive fungal diseases. The kit is intended for professional use only.